TWIN TO TWIN TRANSFUSION SYNDROM AND TWIN ANEMIA POLYCYTEMIA SYNDROM

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Josip Đelmiš, Marina Ivanišević

Department of Obstetrics and Gynecology, Clinical Hospital Center Zagreb,
School of Medicine, University of Zagreb

Key words: monochorionic twins, twin to twin transfusion syndrom, twin anemia polycytemia syndrom
SUMMARY. Twin to Twin Transfusion Syndrome (TTTS) and Twin Anemia and Polycytemia Syndrome (TAPS) are
complications of monochorial twin pregnancy and their common circulation. Through the anastomoses of the placenta
blood vessels, constant changes of blood between the twins result in severe pathology. Twin to twin transfusion syndrome occurs in 10-15% monochorionic pregnancies or in approximately 0.07% of all pregnancies, and Twin anemia
policytemia syndrome occurs in 3-5% monochorionic pregnancies. Both syndromes are the result of an imbalance in
blood fl ow between the fetuses. Twin to twin transfusion syndrome is characterized by the occurrence of polyhydramnion in the twin recipient and the oligohydramion in the twin who serves as donor, while in the case of fetal anemia
polycythemia is a major discrepancy in hemoglobin levels between twins. Fetoscopic laser photocoagulation of the
vascular anastomoses is most successful for the treatment of twin to twin transfusion syndrom, and for the treatment of
twin anemia-polycythema syndrome.